Wang-Buzsaki Model Neuron

Requirements: None
Limitations: None

WB Neuron GUI

The Wang-Buzsaki model uses the Hodgkin-Huxley formalism to describe a single-compartment neuron with sodium and potassium conductances. For the transient sodium current, the activation variable m is assumed fast and substituted by its steady-state function.

Wang XJ, Buzsáki G (1996) Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. J. Neurosci. 16: 6402–6413.

Input Channels

  1. input(0) - Istim : input current (A)

Output Channels

  1. output(0) - Vm : membrane voltage (V)

Parameters

  1. Iapp - applied current (nA)
  2. V0 - voltage (mV)
  3. Cm - membrane capacitance (nF/cm^2)
  4. G_Na_max - max. Na+ conductance density (uS/cm^2)
  5. E_Na - Na+ reversal potential (mV)
  6. G_K_max - max. K+ conductance density (uS/cm^2)
  7. E_K - K+ reversal potential (mV)
  8. G_L - leak channel conductance density (uS/cm^2)
  9. E_L - leak channel reversal potential (mV)
  10. rate - rate of integration (Hz)

States

  1. h - sodium inactivation
  2. n - potassium inactivation
  3. Time - time (s)
NIH grant R01EB029763
RTXI on GitHub