Connor-Stevens Neuron

Requirements: None
Limitations: None

CS Model Neuron GUI

The Connor Stevens model neuron is like the Hodgkin-Huxley neuron, but with slightly different kinetics for the fast sodium and potassium delayed-rectifier channels and an additional A-type potassium channel (Dayan and Abbott, Theoretical Neuroscience, Ch. 6). These changes give the Connor Stevens neuron Type I excitability such that it can achieve arbitrarily low spike rates. This feature may make this model more useful for testing custom modules than the Hodgkin-Huxley model neuron.

Input Channels

  1. input(0) - Iapp : applied current (A)

Output Channels

  1. output(0) - Vm : membrane voltage (V)

Parameters

  1. V0 - initial membrane voltage (mV)
  2. Cm - membrane capacitance (uF/cm^2)
  3. G_Na_max - max. Na+ conductance density (mS/cm^2)
  4. E_Na - Na+ reversal potential (mV)
  5. G_K_max - max. delayed rectifier conductance density (mS/cm^2)
  6. E_K - K+ reversal potential (mV)
  7. G_A_max - max. transient A-type K+ conductance density (mS/cm^2)
  8. E_A - A-type K+ reversal potential (mV)
  9. G_L - leak channel conductance (mS/cm^2)
  10. E_L - potential across leak channel (mV)
  11. rate - rate of integration (Hz)

States

  1. m - sodium activation
  2. h - sodium inactivation
  3. n - potassium inactivation
  4. a - A-type potassium activation
  5. b - A-type potassium inactivation
  6. IKA - A-type potassium current
  7. Time - time (s)
NIH grant R01EB029763
RTXI on GitHub